Orilissa (Elagolix)

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Product Details


Orilissa (Elagolix) is prescribed to women for the relief of moderate to severe pain associated with a condition called endometriosis. Endometriosis refers to the abnormal growth of uterine tissue in locations outside of the womb, such as on the surface of the uterus, ovaries, or other organs. This condition can cause various symptoms including painful, heavy, or irregular menstrual periods, pain during or after sexual intercourse, and infertility.

Elagolix functions by reducing the production of specific hormones in the body, thereby resulting in decreased levels of female sex hormones (estrogens). This reduction in hormone levels may ease some of the symptoms caused by endometriosis. When considering treatment options for endometriosis, there are several important factors to consider like effectiveness, potential side effects, and the Orilissa cost.


Take this medication orally as directed by your doctor, with or without food.

Take the medication regularly at the same time, usually once or twice daily.

The dosage and duration of treatment depend on your medical condition, response to treatment, and other medications you are taking.

Your doctor may conduct a pregnancy test before starting this medication or advise you to begin taking it within 7 days of the start of your menstrual period to ensure you are not pregnant.

Typically, this medication is taken for up to 6 months or up to 24 months to minimize the risk of bone loss.


The active ingredient in Orilissa is Elagolix Sodium.


Inform your doctor if you have allergies to Elagolix or any other substances.

Before starting this medication, it is important to share your complete medical history with your doctor, especially if you have a history of liver problems, bone loss, or mood disorders such as depression.

Do not use this medication during pregnancy, as it may harm an unborn baby.

Consult your doctor before breastfeeding.


There may be a negative drug interaction between Orilissa and aliskiren, amiodarone, itraconazole, ketoconazole, voriconazole bilastine, cetirizine, loratadine, birth control pills, amlodipine, diltiazem, nifedipine, verapamil, carbamazepine, carvedilol, brentuximab, daunorubicin, doxorubicin, etoposide, idarubicin, methotrexate, mitotane, vinblastine, vincristine, cimetidine, clobazam, clozapine, cobicistat, colchicine, conivaptan, cyclosporine, dabigatran, dexamethasone, digoxin, dronedarone, edoxaban, eltrombopag, conjugated estrogen, estradiol, ethinyl estradiol, everolimus, gemfibrozil, linagliptin, saxagliptin, sitagliptin, grapefruit juice, daclatasvir, glecaprevir, grazoprevir, ledipasvir, ombitasvir, paritaprevir, velpatasvir, voxilaprevir, efavirenz, etravirine, nevirapine, atazanavir, darunavir, lopinavir, ritonavir, hydrocortisone, idelalisib, leflunomide, lumacaftor and ivacaftor, clarithromycin, erythromycin, midazolam, mifepristone, omeprazole, nadolol, naloxegol, paliperidone, phenobarbital, phenytoin, primidone, bosutinib, crizotinib, dabrafenib, imatinib, pazopanib, prucalopride, quinidine, quinine, rifampin, risperidone, romidepsin, silodosin, sirolimus, atorvastatin, lovastatin, simvastatin, stiripentol, tacrolimus, teriflunomide, tolvaptan.

Side Effects

The typical Orilissa side effects include:

  • Fluctuations in body temperature characterized by sudden heat sensations
  • Perspiration experienced during nighttime
  • Absence or irregularity of menstrual cycles
  • Alterations in emotional state
  • Aching or discomfort in the joints
  • Feeling of sickness or queasiness
  • Headache
  • Difficulty falling asleep or staying asleep.

There may be other potential adverse reactions associated with Orilissa. Before you buy Orilissa, make sure you talk to your doctor for medical advice about these side effects.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

Product Code : 13919

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