Janumet XR (Sitagliptin / Metformin)

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Product Details


Janumet XR is a prescription medication for lowering blood sugar and improved glycemic control and is the extended-release version of Janumet for longer lasting blood sugar management. It is a combination of two active ingredients with Sitagliptin increasing the production of GLP-1 and GIP hormones to promote more pancreatic insulin production while the added Metformin Hydrochloride lowers the amount of glucose from food and increases insulin responsiveness. Janumet XR medication may be better for patients who need the added insulin production of Sitagliptin as well as the more gradual and longer release of Metformin Hydrochloride rather than standard Metformin.


Standard dosage is to take Janumet XR medication 1x daily with a meal. Dosage may vary based on doctor’s specifications and you should always take your medication as indicated in your prescription.


The active ingredients in Janumet XR are Sitagliptin and Metformin Hydrochloride.


Tell your doctor if you have any history of liver or kidney disease, breathing difficulty conditions like obstructive lung disease or severe asthma, blood problems like anemia or vitamin B12 deficiency, pancreatitis, or gallstones before starting on Janumet XR.

Patients with upcoming x-ray or other scans using iodinated contrast may need to postpone their starting to take Janumet XR.

Medication use may not be appropriate for patients using diuretics (water pills).

Janumet XR side effects may be more pronounced in older adults.

Metformin hydrochloride can cause changes in the menstrual cycle (promote ovulation) and increase the risk of becoming pregnant.


There is the possibility of negative drug interactions between Janumet XR and other RX or OTC medications, including hushart, ranolazine, vandetanib, dolutegravir, cimetidine, and metropolol. Tell your doctor of all medications and OTC supplements before receiving a prescription and proceeding to buy Janumet XR online.

Side Effects

Side effects from using Janumet XR are possible, and some users may experience nausea, vomiting, stomach upset, diarrhea, headache, weakness, or a metallic taste in the mouth. If side effects are experienced you may want to discontinue use and speak to your doctor again regarding Type 2 oral diabetes medication alternatives.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your healthcare professional for medical advice and treatment.

Product Code : 13882

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